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Healtheuniversity > English > Cardiac College > Treat Heart Disease > Heart Medicines > Sodium Glucose Co-transporter 2 (SGLT2) Inhibitors

Sodium Glucose Co-transporter 2 (SGLT2) Inhibitors


  • Helps people who have heart failure live longer and feel better
  • Lowers the chance that you will be hospitalized to treat heart failure
  • Lowers blood sugar in people who have diabetes
  • Lowers the chance that you will develop worsening kidney failure and cardiovascular disease


  • SGLT2 Inhibitors help your kidneys remove sodium (salt) and glucose (sugar) from your blood. With less sodium and glucose, you will retain less fluid and lower your blood pressure.
  • For people living with diabetes, excess sugar (glucose) from your blood is removed from your body in your pee (urine) and this lowers your blood sugar levels.

Potential Side Effects

  • Dizziness or feeling lightheaded
  • Increased amount of pee (urine)
  • Genital yeast infections (in all genders) that need treatment
  • Dehydration (too little water in your body)
  • Low blood sugar
  • Ketoacidosis (when chemicals called ketones build up in your blood)

Common Names

  • Canagliflozin (Canagliflozin)​
  • Dapagliflozin (Forxiga)
  • Empagliflozin (Jardiance)


In the past, SGLT2 Inhibitors were only prescribed to people living with type 2 diabetes. Recent studies show that they can also help people who are living with heart failure.​

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