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Healtheuniversity > English > Cardiac College > Treat Heart Disease > Heart Medicines > Aldosterone antagonists (Mineralocorticoid receptor antagonists- MRAs)

Aldosterone antagonists (Mineralocorticoid receptor antagonists- MRAs)


  • Helps your heart muscle to heal
  • Can prevent further damage to an already weakened heart
  • Can help to control high blood pressure


  • ​​​Prescribed for people who have high blood pressure or heart failure
  • Helps people living with heart failure or high blood pressure get rid of extra fluid from their bodies
  • Reduces extra fluid buildup in your lungs, lower legs, and ankles

Potential Side Effects

  • Swollen and enlarged breast
  • Dry mouth
  • Rash
  • Low blood pressure
  • Dizziness
  • Nausea (upset stomach)
  • High potassium levels in your blood

Common Names

  • Eplerenone (Inspra)
  • Spirinolactone (Aldactone)

Last Reviewed: